BDBM494813 N-(4-fluorobicyclo[4.2.0]octa- 1,3,5-trien-7-yl)-N'-hydroxy-4- {[1-(hydroxyacetyl)azetidin-3- yl]sulfanyl}-1,2,5-oxadiazole- 3-carboximidamide::US10988487, Example 209

SMILES OCC(=O)N1CC(C1)Sc1nonc1\C(NC1Cc2ccc(F)cc12)=N\O

InChI Key InChIKey=SNARZDZECRBQBC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 494813   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM494813(US10988487, Example 209 | N-(4-fluorobicyclo[4.2.0...)
Affinity DataIC50: 60.9nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
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