BDBM494784 2-[(4-{N-[(1S)-6-fluoro-2,3- dihydro-1H-inden-1-yl]-N'- hydroxycarbamimidoyl}-1,2,5- oxadiazol-3-yl)sulfanyl]-N-(2- hydroxypropyl)acetamide::US10988487, Example 180

SMILES CC(O)CNC(=O)CSc1nonc1\C(N[C@H]1CCc2ccc(F)cc12)=N\O

InChI Key InChIKey=IAXNRLMLGKVMCI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 494784   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM494784(US10988487, Example 180 | 2-[(4-{N-[(1S)-6-fluoro-...)
Affinity DataIC50: 55.4nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
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