BDBM494781 N~2~-(4-{N-[(7S)-4- chlorobicyclo[4.2.0]octa-1,3,5- trien-7-yl]-N'- hydroxycarbamimidoyl}-1,2,5- oxadiazol-3-yl)-N-(2- hydroxyethyl)glycinamide::US10988487, Example 177

SMILES OCCNC(=O)CNc1nonc1\C(N[C@H]1Cc2ccc(Cl)cc12)=N\O

InChI Key InChIKey=UHZLQQBIRHQZEC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 494781   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM494781(US10988487, Example 177 | N~2~-(4-{N-[(7S)-4- chlo...)
Affinity DataIC50: 49nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
Go to US Patent