BDBM494759 2-((4-(N-(4- fluorobicyclo[4.2.0]octa-1(6),2,4- trien-7-yl)-N''- hydroxycarbamimidoyl)-1,2,5- oxadiazol-3-yl)amino)-N- isopropylacetamide (peak 1)::US10988487, Example 155::US10988487, Example 156

SMILES CC(C)NC(=O)CNc1nonc1\C(NC1Cc2ccc(F)cc12)=N\O

InChI Key InChIKey=RYRIQMKMRFBIAK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 494759   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM494759(US10988487, Example 155 | US10988487, Example 156 ...)
Affinity DataIC50: 65.9nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM494759(US10988487, Example 155 | US10988487, Example 156 ...)
Affinity DataIC50: 1.02E+3nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
Go to US Patent