BDBM494697 N-cyclopropyl-2-((4-(N-(4- fluorobicyclo[4.2.0]octa-1(6),2,4-trien- 7-yl)-N''-hydroxycarbamimidoyl)- 1,2,5-oxadiazol-3-yl)thio)acetamide (peak 1)::US10988487, Example 93::US10988487, Example 94

SMILES O\N=C(/NC1Cc2ccc(F)cc12)c1nonc1SCC(=O)NC1CC1

InChI Key InChIKey=AWTBYPYCUZMVQL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 494697   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM494697(US10988487, Example 93 | N-cyclopropyl-2-((4-(N-(4...)
Affinity DataIC50: 59nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM494697(US10988487, Example 93 | N-cyclopropyl-2-((4-(N-(4...)
Affinity DataIC50: 2.76E+3nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
Go to US Patent