BDBM494550 US10988482, Compound 54

SMILES C[C@]1(O)CC[C@@H](CC1)Nc1nc(Nc2cc(ns2)C(=O)NCC2CCNCC2)nc2ccsc12

InChI Key InChIKey=JXHLIVWLLNNPRP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 494550   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Beijing Hanmi Pharmaceutical

US Patent
LigandPNGBDBM494550(US10988482, Compound 54)
Affinity DataIC50: 100nMAssay Description:IRAK4 kinase (purchased from Life Technologies, Cat. No.: PR5612U) was diluted to 2 folds of the final concentration (the final concentration is 0.76...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
Go to US Patent