BDBM494497 N-(2-(((1S,2S)-2- hydroxycyclopentyl)methyl)- 6-morpholino-1- oxoisoindolin-5- yl)pyrazolo[1,5-a] pyrimidine-3- carboxamide::US10988478, Example 559

SMILES O[C@H]1CCC[C@H]1CN1Cc2cc(NC(=O)c3cnn4cccnc34)c(cc2C1=O)N1CCOCC1

InChI Key InChIKey=AFAGLQHSDLEIAU-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 494497   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM494497(US10988478, Example 559 | N-(2-(((1S,2S)-2- hydrox...)
Affinity DataKi:  2.20nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
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