BDBM494286 US10988478, Example 335::US10988478, Example 336

SMILES C[C@@]1(CO)Cc2cc(NC(=O)c3cnn4cccnc34)c(cc2O1)N1CCC(CC1)C#N

InChI Key InChIKey=QQEJFPKGJMGCFG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 494286   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM494286(US10988478, Example 335 | US10988478, Example 336)
Affinity DataKi:  2nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
Go to US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM494286(US10988478, Example 335 | US10988478, Example 336)
Affinity DataKi:  3nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
Go to US Patent