BDBM494235 N-[6-[4-(2,2- Difluoroethyl)piperazin-1- yl]-2-[(2R)-2-fluoro-3- hydroxy-3-methyl-butyl]-1- oxo-isoindolin-5-yl]-6- methyl-pyrazolo[1,5- a]pyrimidine-3-carboxamide::US10988478, Example 284

SMILES Cc1cnc2c(cnn2c1)C(=O)Nc1cc2CN(C[C@@H](F)C(C)(C)O)C(=O)c2cc1N1CCN(CC(F)F)CC1

InChI Key InChIKey=IJQWEUXPYDVLCS-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 494235   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM494235(US10988478, Example 284 | N-[6-[4-(2,2- Difluoroet...)
Affinity DataKi:  2nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
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