BDBM494232 N-[6-[4-(2-Amino-2-oxo- ethyl)piperazin-1-yl]-2-(1- methyl-4-piperidyl)-1-oxo- isoindolin-5- yl]pyrazolo[1,5- a]pyrimidine-3-carboxamide::US10988478, Example 281

SMILES CN1CCC(CC1)N1Cc2cc(NC(=O)c3cnn4cccnc34)c(cc2C1=O)N1CCN(CC(N)=O)CC1

InChI Key InChIKey=QGMXWIKBAKAYES-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 494232   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM494232(US10988478, Example 281 | N-[6-[4-(2-Amino-2-oxo- ...)
Affinity DataKi:  2.40nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
Go to US Patent