BDBM494222 6-Chloro-N-[2-[(2R)-2- fluoro-3-hydroxy-3-methyl- butyl]-6-morpholino-1-oxo- isoindolin-5- yl]pyrazolo[1,5- a]pyrimidine-3-carboxamide::US10988478, Example 271

SMILES CC(C)(O)[C@H](F)CN1Cc2cc(NC(=O)c3cnn4cc(Cl)cnc34)c(cc2C1=O)N1CCOCC1

InChI Key InChIKey=MZAYXWUJRYYMPL-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 494222   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM494222(US10988478, Example 271 | 6-Chloro-N-[2-[(2R)-2- f...)
Affinity DataKi:  1.70nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
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