BDBM494212 N-[6-(3,3- Difluoropyrrolidin-1-yl)-2- [(2R)-2-fluoro-3-hydroxy-3- methyl-butyl]-1-oxo- isoindolin-5- yl]pyrazolo[1,5- a]pyrimidine-3-carboxamide::US10988478, Example 261

SMILES CC(C)(O)[C@H](F)CN1Cc2cc(NC(=O)c3cnn4cccnc34)c(cc2C1=O)N1CCC(F)(F)C1

InChI Key InChIKey=KHTKDSBPTWFVQV-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 494212   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM494212(US10988478, Example 261 | N-[6-(3,3- Difluoropyrro...)
Affinity DataKi:  2nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
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