BDBM494044 (R)—N-(2-(hydroxymethyl)-6-(4-(hydroxymethyl)piperidin-1-yl)-2-methyl-2,3-dihydrobenzofuran-5-yl)-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide::US10988478, Example 92

SMILES Cc1cnc2c(cnn2c1)C(=O)Nc1cc2C[C@](C)(CO)Oc2cc1N1CCC(CO)CC1

InChI Key InChIKey=PYLAWUUVOVWLLQ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 494044   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM494044(US10988478, Example 92 | (R)—N-(2-(hydroxymet...)
Affinity DataKi:  2.30nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
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