BDBM493950 N-[2-(hydroxymethyl)-6-[4- (hydroxymethyl)-1-piperidyl]-2- methyl-3H-benzofuran-5-yl]-6-methyl- pyrazolo[1,5-a]pyrimidine-3- carboxamide::US10988478, Example 16

SMILES Cc1cnc2c(cnn2c1)C(=O)Nc1cc2CC(C)(CO)Oc2cc1N1CCC(CO)CC1

InChI Key InChIKey=PYLAWUUVOVWLLQ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 493950   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM493950(US10988478, Example 16 | N-[2-(hydroxymethyl)-6-[4...)
Affinity DataKi:  1.90nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
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