BDBM493937 N-[6-[4-(2,2-difluoroethyl)piperazin-1- yl]-2,2-dimethyl-3H-benzofuran-5- yl]pyrazolo[1,5-a]pyrimidine-3- carboxamide::US10988478, Example 8::US10988478, Example 89

SMILES CC1(C)Cc2cc(NC(=O)c3cnn4cccnc34)c(cc2O1)N1CCN(CC(F)F)CC1

InChI Key InChIKey=WFQAMUFXBXJWTQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 493937   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM493937(US10988478, Example 8 | N-[6-[4-(2,2-difluoroethyl...)
Affinity DataKi:  2.30nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
Go to US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM493937(US10988478, Example 8 | N-[6-[4-(2,2-difluoroethyl...)
Affinity DataKi:  26nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
Go to US Patent