BDBM493768 US10988455, Example 1(clxxix)

SMILES Cc1cc(cc(n1)C(F)F)-c1nnc(N)nc1-c1ccccc1

InChI Key InChIKey=MNGOGRYXCCAACX-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 493768   

TargetAdenosine receptor A2a(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM493768(US10988455, Example 1(clxxix))
Affinity DataKi:  2.40nMAssay Description:All test compounds were prepared as a stock solution of 10 mM in 100% DMSO.Inhibition binding assays were performed using 2.5 μg of membranes pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A1(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM493768(US10988455, Example 1(clxxix))
Affinity DataKi:  30.2nMAssay Description:All test compounds were prepared as a stock solution of 10 mM in 100% DMSO.Inhibition binding assays were performed using 2.5 μg of membranes pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2021
Entry Details
Go to US Patent