BDBM493295 3-cyclopropyl-6-[(5-fluoropyridin-2-yl)methyl]-1-[(1R)-1-[6- (trifluoromethyl)pyridin-3-yl]propyl]1H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one;::US10981916, Example 22

SMILES CC[C@H](c1ccc(nc1)C(F)(F)F)n1nc(C2CC2)c2c1nc(Cc1ccc(F)cn1)[nH]c2=O

InChI Key InChIKey=ISTDMRJUNIMXGU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 493295   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM493295(US10981916, Example 22 | 3-cyclopropyl-6-[(5-fluor...)
Affinity DataIC50: 5.50E+3nMAssay Description:An IMAP TR-FRET-based phosphodiesterase assay was developed using the PDE2A isoform. IMAP technology is based on high-affinity binding of phosphate b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2021
Entry Details
Go to US Patent