BDBM493134 3-cyclopropyl-6-[(5-methoxypyridin-2-yl)methyl]-1-[(1R)-1-[6- (trifluoromethyl)pyridin-3-yl]ethyl]-1H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one;::US10981916, Example 6

SMILES COc1ccc(Cc2nc3n(nc(C4CC4)c3c(=O)[nH]2)[C@H](C)c2ccc(nc2)C(F)(F)F)nc1

InChI Key InChIKey=HPIZHEITUPKAOO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 493134   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM493134(US10981916, Example 6 | 3-cyclopropyl-6-[(5-methox...)
Affinity DataIC50: 550nMAssay Description:An IMAP TR-FRET-based phosphodiesterase assay was developed using the PDE2A isoform. IMAP technology is based on high-affinity binding of phosphate b...More data for this Ligand-Target Pair
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Date in BDB:
10/27/2021
Entry Details
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