BDBM492977 US10981898, Example 79

SMILES CC(C)(O)c1cc2C(=O)N(Cc3ccc(Cl)cc3Br)[C@](OCC3(CC3)C#N)(c2c(F)c1)c1ccc(Cl)cc1

InChI Key InChIKey=HONPZSDBHRBCAL-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492977   

TargetCellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188](Human)
Astex Therapeutics

US Patent

LigandBDBM492977(US10981898, Example 79)Copy SMILESCopy InChI

Affinity DataIC50: 2.20nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/26/2021
Entry Details
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