BDBM492895 N-((6-amino-2,4- dimethylpyridin-3- yl)methyl)-2-((3- chloroquinolin-6- yl)methyl)pyrimidine-4- carboxamide::US10981893, Example 24

SMILES Cc1cc(N)nc(C)c1CNC(=O)c1ccnc(Cc2ccc3ncc(Cl)cc3c2)n1

InChI Key InChIKey=GSSVWNIRIUATGU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492895   

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandPNGBDBM492895(US10981893, Example 24 | N-((6-amino-2,4- dimethyl...)
Affinity DataIC50: 100nMAssay Description:The ability of the compounds disclosed herein to inhibit human plasma kallikrein activity was quantified according to the procedures below.A 10 mM so...More data for this Ligand-Target Pair
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Date in BDB:
10/26/2021
Entry Details
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