BDBM492883 2-(5-chloro-1H-indazol- 3-yl)-2-(5-(4-((2- oxopyridin-1(2H)- yl)methyl)benzyl) nicotinamido)acetic acid::US10981893, Example 12

SMILES OC(=O)C(NC(=O)c1cncc(Cc2ccc(Cn3ccccc3=O)cc2)c1)c1n[nH]c2ccc(Cl)cc12

InChI Key InChIKey=SMDORXCKKYMGQG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492883   

TargetPlasma kallikrein(Human)
Attune Pharmaceuticals

US Patent
LigandPNGBDBM492883(US10981893, Example 12 | 2-(5-chloro-1H-indazol- 3...)
Affinity DataIC50: 5.50E+3nMAssay Description:The ability of the compounds disclosed herein to inhibit human plasma kallikrein activity was quantified according to the procedures below.A 10 mM so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
US Patent