BDBM492601 6-Amino-3-(4-chlorophenyl)-4-(3-iodo-4-methoxyphenyl)-2,4-dihydropyrano [2,3-c]pyrazole-5-carbonitrilem ::US10980781, Compound 7i::US10980781, Entry 29::US11617738, Compound 7i

SMILES COc1ccc(cc1I)C1c2c(OC(N)=C1C#N)n[nH]c2-c1ccc(Cl)cc1

InChI Key InChIKey=YJRBBWPHBGBIOZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 492601   

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM492601(US10980781, Entry 29 | 6-Amino-3-(4-chlorophenyl)-...)
Affinity DataIC50: 1.50E+4nMAssay Description:The lyophilized compounds were re-suspended in 100% DMSO to a stock concentration of 10 mM and stored at −20° C. Where Ratesample is the initia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM492601(US10980781, Entry 29 | 6-Amino-3-(4-chlorophenyl)-...)
Affinity DataIC50: 1.50E+4nMAssay Description:The percent inhibition of USP7 at 100 μM of each compound was determined prior to the determination of IC50 values. The final concentration of s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
Go to US Patent