BDBM492592 6-Amino-4-(3-iodo-4-methoxyphenyl)-3-(thiophen-2-yl)-2,4-dihydropyrano [2,3-c]pyrazole-5-carbonitrile::US10980781, Compound 6u::US10980781, Compound 7b::US10980781, Entry 19::US11617738, Compound 6u

SMILES COc1ccc(cc1I)C1c2c(OC(N)=C1C#N)n[nH]c2-c1cccs1

InChI Key InChIKey=YRNIFGNLCVSLSU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 492592   

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM492592(US10980781, Compound 6u | US10980781, Entry 19 | U...)
Affinity DataIC50: 1.80E+3nMAssay Description:The lyophilized compounds were re-suspended in 100% DMSO to a stock concentration of 10 mM and stored at −20° C. Where Ratesample is the initia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM492592(US10980781, Compound 6u | US10980781, Entry 19 | U...)
Affinity DataIC50: 5.60E+3nMAssay Description:The lyophilized compounds were re-suspended in 100% DMSO to a stock concentration of 10 mM and stored at −20° C. Where Ratesample is the initia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM492592(US10980781, Compound 6u | US10980781, Entry 19 | U...)
Affinity DataIC50: 1.80E+3nMAssay Description:The percent inhibition of USP7 at 100 μM of each compound was determined prior to the determination of IC50 values. The final concentration of s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
Go to US Patent