BDBM492586 6-Amino-4-(3-bromo-4-(prop-2-yn-1-yloxy)phenyl)-3-(thiophen-2-yl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile::US10980781, Compound 6n::US11617738, Compound 6n

SMILES NC1=C(C#N)C(c2c(O1)n[nH]c2-c1cccs1)c1ccc(OCC#C)c(Br)c1

InChI Key InChIKey=QHEORVVUKDAUIK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 492586   

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM492586(6-Amino-4-(3-bromo-4-(prop-2-yn-1-yloxy)phenyl)-3-...)
Affinity DataIC50: 4.50E+3nMAssay Description:The lyophilized compounds were re-suspended in 100% DMSO to a stock concentration of 10 mM and stored at −20° C. Where Ratesample is the initia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
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TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM492586(6-Amino-4-(3-bromo-4-(prop-2-yn-1-yloxy)phenyl)-3-...)
Affinity DataIC50: 4.50E+3nMAssay Description:The percent inhibition of USP7 at 100 μM of each compound was determined prior to the determination of IC50 values. The final concentration of s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
Go to US Patent