BDBM492584 6-Amino-4-(3-bromo-4-methoxyphenyl)-3-(thiophen-2-yl)-2,4-dihydropyrano [2,3-c]pyrazole-5-carbonitrile::US10980781, Compound 6a::US10980781, Compound 7a::US10980781, Entry 1::US11617738, Compound 6a

SMILES COc1ccc(cc1Br)C1c2c(OC(N)=C1C#N)n[nH]c2-c1cccs1

InChI Key InChIKey=GUQLPMBJIGKMQI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 492584   

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM492584(US10980781, Compound 6a | US10980781, Entry 1 | US...)
Affinity DataIC50: 3.70E+3nMAssay Description:The lyophilized compounds were re-suspended in 100% DMSO to a stock concentration of 10 mM and stored at −20° C. Where Ratesample is the initia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM492584(US10980781, Compound 6a | US10980781, Entry 1 | US...)
Affinity DataIC50: 8.10E+3nMAssay Description:The lyophilized compounds were re-suspended in 100% DMSO to a stock concentration of 10 mM and stored at −20° C. Where Ratesample is the initia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM492584(US10980781, Compound 6a | US10980781, Entry 1 | US...)
Affinity DataIC50: 3.70E+3nMAssay Description:The percent inhibition of USP7 at 100 μM of each compound was determined prior to the determination of IC50 values. The final concentration of s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
Go to US Patent