BDBM492561 N-{4-[6-(1-methylethyl)- 7-oxo-4,7- dihydro[1,2,4]triazolo[1,5- a]pyrimidin-5- yl]phenyl}cyclopropanesulfonamide::US10975084, Example 11-124

SMILES CC(C)c1c([nH]c2ncnn2c1=O)-c1ccc(NS(=O)(=O)C2CC2)cc1

InChI Key InChIKey=CHCDLDHGQVOOST-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492561   

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492561(US10975084, Example 11-124 | N-{4-[6-(1-methylethy...)
Affinity DataIC50: 8.76nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
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Date in BDB:
10/20/2021
Entry Details
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