BDBM492488 5-[1-(3-chlorophenyl)- 1H-pyrazol-4-yl]-6-(1- methylethyl)[1,2,4]triazolo[1,5- a]pyrimidin-7(4H)-one::US10975084, Example 11-51

SMILES CC(C)c1c([nH]c2ncnn2c1=O)-c1cnn(c1)-c1cccc(Cl)c1

InChI Key InChIKey=HSNJAABZLMWACZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 492488   

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492488(US10975084, Example 11-51 | 5-[1-(3-chlorophenyl)-...)
Affinity DataIC50: 9.66nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent