BDBM491856 N-(2-(1H-indol-3- yl)-1-phenylethyl)- 2-(4-methyl- piperazin-1-yl)- thiazole-5- carboxamide::US10975066, Example 20

SMILES CN1CCN(CC1)c1ncc(s1)C(=O)NC(Cc1c[nH]c2ccccc12)c1ccccc1

InChI Key InChIKey=WKTCYRQNRYQWDD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 491856   

TargetAlpha-synuclein(Human)
Ucb Biopharma

US Patent
LigandPNGBDBM491856(US10975066, Example 20 | N-(2-(1H-indol-3- yl)-1-p...)
Affinity DataIC50: 2.00E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent