BDBM491851 N-(1-(1H-indol- 3-yl)-5-methyl- hexan-2-yl)-2-(4- methylpiperazin- 1-yl)thiazole-5- carboxamide::US10975066, Example 14

SMILES CC(C)CCC(Cc1c[nH]c2ccccc12)NC(=O)c1cnc(s1)N1CCN(C)CC1

InChI Key InChIKey=XPKHGLLLQIGKGI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 491851   

TargetAlpha-synuclein(Human)
Ucb Biopharma

US Patent
LigandPNGBDBM491851(US10975066, Example 14 | N-(1-(1H-indol- 3-yl)-5-m...)
Affinity DataIC50: 1.40E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent