BDBM491850 N-(1-(1H-indol- 3-yl)hexan-2-yl)- 2-(cis-3,4,5- trimethylpiperazin- 1-yl)thiazole-5- carboxamide::US10975066, Example 13

SMILES CCCCC(Cc1c[nH]c2ccccc12)NC(=O)c1cnc(s1)N1C[C@H](C)N(C)[C@H](C)C1

InChI Key InChIKey=HRZGXDGHCWZQSM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 491850   

TargetAlpha-synuclein(Human)
Ucb Biopharma

US Patent
LigandPNGBDBM491850(US10975066, Example 13 | N-(1-(1H-indol- 3-yl)hexa...)
Affinity DataIC50: 1.20E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent