BDBM491849 N-(1-(1H-indol-3- yl)hexan-2-yl)-2- (3,3,4-trimethyl- piperazin-1-yl)- thiazole-5- carboxamide::US10975066, Example 12

SMILES CCCCC(Cc1c[nH]c2ccccc12)NC(=O)c1cnc(s1)N1CCN(C)C(C)(C)C1

InChI Key InChIKey=AAGLOKOWWZJTEB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 491849   

TargetAlpha-synuclein(Human)
Ucb Biopharma

US Patent
LigandPNGBDBM491849(US10975066, Example 12 | N-(1-(1H-indol-3- yl)hexa...)
Affinity DataIC50: 1.50E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent