BDBM491843 N-(1-(1H-indol-3- yl)hexan-2-yl)- 2-(4-(2-methoxy- ethyl)piperazin-1- yl)thiazole-5- carboxamide::US10975066, Example 6

SMILES CCCCC(Cc1c[nH]c2ccccc12)NC(=O)c1cnc(s1)N1CCN(CCOC)CC1

InChI Key InChIKey=SHULKHNFRMOYMY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 491843   

TargetAlpha-synuclein(Human)
Ucb Biopharma

US Patent
LigandPNGBDBM491843(US10975066, Example 6 | N-(1-(1H-indol-3- yl)hexan...)
Affinity DataIC50: 1.10E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent