BDBM491841 N-(1-(1H-indol-3- yl)hexan-2-yl)-2- (4-(tert-butyl)- piperazin-1-yl)- thiazole-5- carboxamide::US10975066, Example 4

SMILES CCCCC(Cc1c[nH]c2ccccc12)NC(=O)c1cnc(s1)N1CCN(CC1)C(C)(C)C

InChI Key InChIKey=ZRMQNUDRNMCRHS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 491841   

TargetAlpha-synuclein(Human)
Ucb Biopharma

US Patent
LigandPNGBDBM491841(US10975066, Example 4 | N-(1-(1H-indol-3- yl)hexan...)
Affinity DataIC50: 1.50E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent