BDBM491801 4-Chloro-5-(4-(difluoromethoxy)-6-(((R*)-1,1,1-trifluoropentan-3-yl)amino)pyridin-3-yl)-1-ethyl-N-(((1s,4S)-1-hydroxy-4-(methylsulfonyl)cyclohexyl)methyl)-1H-pyrazole-3-carboxamide::US10975057, Example 89

SMILES CC[C@H](CC(F)(F)F)Nc1cc(OC(F)F)c(cn1)-c1c(Cl)c(nn1CC)C(=O)NC[C@@]1(O)CC[C@@H](CC1)S(C)(=O)=O

InChI Key InChIKey=DDBCZGXUUVTEKV-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 491801   

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM491801(US10975057, Example 89 | 4-Chloro-5-(4-(difluorome...)
Affinity DataKd:  23nMAssay Description:For the RORγt construct used in the ThermoFluor assay, numbering for the nucleotide sequences was based on the reference sequence for human ROR&...More data for this Ligand-Target Pair
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Date in BDB:
10/20/2021
Entry Details
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