BDBM491439 2-((6-((2-amino-2-oxoethyl)(methyl)amino)-3,5-dicyano-4-ethylpyridin-2-yl)thio)-2-phenylacetamide (Single Enantiomer)::US10975056, Example 413

SMILES CCc1c(C#N)c(S[C@@H](C(N)=O)c2ccccc2)nc(N(C)CC(N)=O)c1C#N

InChI Key InChIKey=QNAWNFWIFHMERM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 491439   

TargetDNA (cytosine-5)-methyltransferase 1(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM491439(US10975056, Example 413 | 2-((6-((2-amino-2-oxoeth...)
Affinity DataIC50: 320nMAssay Description:Biochemical activity of DNMT1 analyzed using SPA technology. Plates (Griener 784075) were pre-stamped with 100 nL/well of compound (11-point, 3-fold ...More data for this Ligand-Target Pair
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Date in BDB:
10/20/2021
Entry Details
US Patent