BDBM491432 (R)-2-((3,5-Dicyano-6-(4-(dimethylamino)piperidin-1-yl)-4-ethylpyridin-2-yl)thio)-2-phenylacetamide::US10975056, Example 406

SMILES CCc1c(C#N)c(S[C@@H](C(N)=O)c2ccccc2)nc(N2CCC(CC2)N(C)C)c1C#N

InChI Key InChIKey=MELQQCMEXPGRLW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 491432   

TargetDNA (cytosine-5)-methyltransferase 1(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM491432(US10975056, Example 406 | (R)-2-((3,5-Dicyano-6-(4...)
Affinity DataIC50: 320nMAssay Description:Biochemical activity of DNMT1 analyzed using SPA technology. Plates (Griener 784075) were pre-stamped with 100 nL/well of compound (11-point, 3-fold ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
US Patent