BDBM491038 (S)-isopropyl N-(4-(2-bromo-3-phenylbenzyloxy)-5-chloro-2-(pyridin-3-yl-methyleneoxy)benzyl) serinate dihydrochloride::US10975049, Example 6

SMILES CC(C)OC(=O)[C@H](CO)NCc1cc(Cl)c(OCc2cccc(c2Br)-c2ccccc2)cc1OCc1cccnc1

InChI Key InChIKey=OYOSMKDITKQNPZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 491038   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM491038(US10975049, Example 6 | (S)-isopropyl N-(4-(2-brom...)
Affinity DataIC50: 82.3nMAssay Description:In vitro activity evaluation: Cisbio PD-1/PD-L1 binding assay kit was applied for the detection method of in vitro enzymology level.Screening Princip...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Henan University

Curated by ChEMBL
LigandPNGBDBM491038(US10975049, Example 6 | (S)-isopropyl N-(4-(2-brom...)
Affinity DataIC50: 45nMAssay Description:Inhibition of PD-1 (unknown origin)/PD-L1 (unknown origin) interaction by HTRF binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed