BDBM490844 4-Chloro-N-(((1s,4S)-1-hydroxy-4-(methylsulfonyl)cyclohexyl)methyl)-5-(2-methoxy-4-((R*)-3,3,3-trifluoro-2-methylpropyl)phenyl)-1-propyl-1H-pyrazole-3-carboxamide::US10975037, Example 42

SMILES CCCn1nc(C(=O)NC[C@@]2(O)CC[C@@H](CC2)S(C)(=O)=O)c(Cl)c1-c1ccc(C[C@@H](C)C(F)(F)F)cc1OC

InChI Key InChIKey=AJQYIWZMDINEPY-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 490844   

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490844(US10975037, Example 42 | 4-Chloro-N-(((1s,4S)-1-hy...)
Affinity DataKd:  0.420nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
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Date in BDB:
10/20/2021
Entry Details
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