BDBM490843 4-Chloro-5-(2-methoxy-4-((S*)-3,3,3-trifluoro-2-methylpropyl)phenyl)-N-(((1r,4S)-4-(methylsulfonyl)cyclohexyl)methyl)-1-propyl-1H-pyrazole-3-carboxamide::US10975037, Example 41

SMILES CCCn1nc(C(=O)NC[C@H]2CC[C@@H](CC2)S(C)(=O)=O)c(Cl)c1-c1ccc(C[C@H](C)C(F)(F)F)cc1OC

InChI Key InChIKey=UTQPRLWFOYPYFQ-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 490843   

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490843(US10975037, Example 41 | 4-Chloro-5-(2-methoxy-4-(...)
Affinity DataKd:  0.280nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent