BDBM490807 N-(((1R*,2R*,4R*)-2-Amino-1-hydroxy-4-(methylsulfonyl)cyclohexyl)methyl)-4-chloro-5-(2-(difluoromethoxy)-4-(3,3,3-trifluoro-2,2-dimethylpropyl)phenyl)-1-ethyl-1H-pyrazole-3-carboxamide Hydrobromide::US10975037, Example 6

SMILES CCn1nc(C(=O)NC[C@]2(O)CC[C@H](CC2NBr)S(C)(=O)=O)c(Cl)c1-c1ccc(CC(C)(C)C(F)(F)F)cc1OC(F)F

InChI Key InChIKey=BGIXMGNHFGWLGM-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 490807   

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490807(US10975037, Example 6 | N-(((1R*,2R*,4R*)-2-Amino-...)
Affinity DataKd:  2.40nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
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Date in BDB:
10/20/2021
Entry Details
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