BDBM490478 2-({2-[(1S)-1-cyclohexylethoxy]-5-fluoro-4-(3-oxo-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)benzoyl}amino)-3-methylbenzoic acid::US10968216, Example 146

SMILES C[C@H](Oc1cc(c(F)cc1C(=O)Nc1c(C)cccc1C(O)=O)-n1nc2CCCCn2c1=O)C1CCCCC1

InChI Key InChIKey=GINULUQNPZKODR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 490478   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
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US Patent
LigandPNGBDBM490478(US10968216, Example 146 | 2-({2-[(1S)-1-cyclohexyl...)
Affinity DataIC50: 2.5nMAssay Description:Assay 2: The enzymatic assay couples DHODH activity with bleaching of the dye 2,6-Dichlorophenolindophenol (DCIP) (Knecht and Loffler, 1998; Miller e...More data for this Ligand-Target Pair
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Date in BDB:
10/9/2021
Entry Details
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