BDBM490070 (S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amino)-3- (4-methoxyphenyl)-1-oxopropan-2- yl)nicotinamide::US10968172, ID # 19aa

SMILES COc1ccc(C[C@H](NC(=O)c2cccnc2)C(=O)Nc2ccc(cc2)S(=O)(=O)NC(C)(C)C)cc1

InChI Key InChIKey=VTVSDXFHFWCXGW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 490070   

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mitobridge

US Patent
LigandPNGBDBM490070(US10968172, ID # 19aa | (S)-N-(1-((4-(N-(tert- but...)
Affinity DataIC50: 208nMAssay Description:The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
Go to US Patent