BDBM490037 (S)-N-(1-((4-(N-(tert- butyl)sulfamoyl)phenyl)amino)-3- cyclohexyl-1-oxopropan-2-yl)-4- fluorobenzamide::US10968172, ID # 14c::US20250162989, Compound I-294

SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](CC2CCCCC2)NC(=O)c2ccc(F)cc2)cc1

InChI Key InChIKey=PNRIPFQIIIJUQE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 490037   

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mitobridge

US Patent
LigandPNGBDBM490037(US10968172, ID # 14c | (S)-N-(1-((4-(N-(tert- buty...)
Affinity DataIC50: 23nMAssay Description:The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mitobridge

US Patent
LigandPNGBDBM490037(US10968172, ID # 14c | (S)-N-(1-((4-(N-(tert- buty...)
Affinity DataIC50: 20nMAssay Description:Inhibition of USP30 (unknown origin) using Ubiquitin-Rhodamine110-Glycine as substrate incubated for 15 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mitobridge

US Patent
LigandPNGBDBM490037(US10968172, ID # 14c | (S)-N-(1-((4-(N-(tert- buty...)
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2025
Entry Details
Go to US Patent