BDBM490016 (S)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-1- yl)amino)-3-(4-methoxyphenyl)-1- oxopropan-2-yl)benzamide::US10968172, ID # 7f

SMILES COc1ccc(C[C@H](NC(=O)c2ccccc2)C(=O)Nc2cccc3c(cccc23)S(=O)(=O)NC(C)(C)C)cc1

InChI Key InChIKey=UJJUSBGWWZTNAT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 490016   

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mitobridge

US Patent
LigandPNGBDBM490016(US10968172, ID # 7f | (S)-N-(1-((5-(N-(tert- butyl...)
Affinity DataIC50: 89nMAssay Description:The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mitobridge

US Patent
LigandPNGBDBM490016(US10968172, ID # 7f | (S)-N-(1-((5-(N-(tert- butyl...)
Affinity DataIC50: 90nMAssay Description:Inhibition of USP30 (unknown origin) using Ubiquitin-Rhodamine110-Glycine as substrate incubated for 15 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed