BDBM489727 (S)-N-(1-((5-(N-(tert- butyl)sulfamoyl)naphthalen-1- yl)amino)-1-oxo-3-phenylpropan- 2-yl)-4,4-difluorocyclohexane-1- carboxamide::US10968172, ID # 4n

SMILES CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)[C@H](Cc3ccccc3)NC(=O)C3CCC(F)(F)CC3)cccc12

InChI Key InChIKey=HGGBELOYWPIXBO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 489727   

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mitobridge

US Patent
LigandPNGBDBM489727(US10968172, ID # 4n | (S)-N-(1-((5-(N-(tert- butyl...)
Affinity DataIC50: 98nMAssay Description:The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mitobridge

US Patent
LigandPNGBDBM489727(US10968172, ID # 4n | (S)-N-(1-((5-(N-(tert- butyl...)
Affinity DataIC50: 100nMAssay Description:Inhibition of USP30 (unknown origin) using Ubiquitin-Rhodamine110-Glycine as substrate incubated for 15 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed