BDBM489644 (4-((2S,4R)-1-((5- methoxy-7-methyl- 1H-indol-4-yl)- methyl)-4-methyl- piperidin-2-yl)phenyl- (methyl)phosphinic acid::US10961252, Cmp No. 29::US11248000, Cmp No. 29

SMILES COc1cc(C)c2[nH]ccc2c1CN1CC[C@@H](C)C[C@H]1c1ccc(cc1)P(C)(O)=O

InChI Key InChIKey=RVRPLMSJKKCNSI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 489644   

TargetComplement factor B(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM489644(US10961252, Cmp No. 29 | (4-((2S,4R)-1-((5- methox...)
Affinity DataIC50: 1.00E+3nMAssay Description:CVF-Bb complex is prepared from purified cobra venom factor (1 μM); human Complement factor B and human Complement factor D are available from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
Go to US Patent

TargetCobra venom factor/Complement factor B/Complement factor D(Monocled cobra)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM489644(US10961252, Cmp No. 29 | (4-((2S,4R)-1-((5- methox...)
Affinity DataIC50: 1.00E+3nMAssay Description:CVF-Bb complex is prepared from purified cobra venom factor (1 μM); human Complement factor B and human Complement factor D are available from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
Go to US Patent