BDBM489637 US10961252, Cmp No. 23::US11248000, Cmp No. 23::imino(4-((2R,4S)-1- ((5-methoxy-7- methyl-1H-indol-4- yl)methyl)-4-methyl- piperidin-2-yl)- phenyl)(methyl)-16- sulfanone

SMILES COc1cc(C)c2[nH]ccc2c1CN1CC[C@H](C)C[C@@H]1c1ccc(cc1)S(C)(=N)=O

InChI Key InChIKey=NJRAAMZBXVDEOK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 489637   

TargetComplement factor B(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM489637(US10961252, Cmp No. 23 | imino(4-((2R,4S)-1- ((5-m...)
Affinity DataIC50: 1.00E+4nMAssay Description:CVF-Bb complex is prepared from purified cobra venom factor (1 μM); human Complement factor B and human Complement factor D are available from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
Go to US Patent

TargetCobra venom factor/Complement factor B/Complement factor D(Monocled cobra)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM489637(US10961252, Cmp No. 23 | imino(4-((2R,4S)-1- ((5-m...)
Affinity DataIC50: 1.00E+4nMAssay Description:CVF-Bb complex is prepared from purified cobra venom factor (1 μM); human Complement factor B and human Complement factor D are available from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
Go to US Patent