BDBM489634 (1R,4s)-4-((S)-1-((5- methoxy-7-methyl- 1H-indol-4-yl)- methyl)piperidin-2- yl)cyclohexane-1- carboxylic acid::US10961252, Cmp No. 20::US11248000, Cmp No. 20

SMILES COc1cc(C)c2[nH]ccc2c1CN1CCCC[C@H]1C1CC[C@@H](CC1)C(O)=O

InChI Key InChIKey=AILBHMHAFJAHON-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 489634   

TargetComplement factor B(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM489634(US10961252, Cmp No. 20 | (1R,4s)-4-((S)-1-((5- met...)
Affinity DataIC50: 1.00E+4nMAssay Description:CVF-Bb complex is prepared from purified cobra venom factor (1 μM); human Complement factor B and human Complement factor D are available from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
Go to US Patent

TargetCobra venom factor/Complement factor B/Complement factor D(Monocled cobra)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM489634(US10961252, Cmp No. 20 | (1R,4s)-4-((S)-1-((5- met...)
Affinity DataIC50: 1.00E+4nMAssay Description:CVF-Bb complex is prepared from purified cobra venom factor (1 μM); human Complement factor B and human Complement factor D are available from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
Go to US Patent