BDBM489626 1-(3-(4-amino-8- fluoro-6,7-dimethoxy- quinazolin-2-yl)-3,8- diazabicyclo[3.2.1]- octan-8-yl)-3-(4- fluorophenyl)prop- 2-en-1-one::US10961252, Cmp No. 14::US11248000, Cmp No. 14

SMILES COc1cc2c(N)nc(nc2c(F)c1OC)N1CC2CCC(C1)N2C(=O)C=Cc1ccc(F)cc1

InChI Key InChIKey=ORQWAVRJKBWEFQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 489626   

TargetComplement factor B(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM489626(US10961252, Cmp No. 14 | 1-(3-(4-amino-8- fluoro-6...)
Affinity DataIC50: 1.00E+4nMAssay Description:CVF-Bb complex is prepared from purified cobra venom factor (1 μM); human Complement factor B and human Complement factor D are available from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
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TargetCobra venom factor/Complement factor B/Complement factor D(Monocled cobra)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM489626(US10961252, Cmp No. 14 | 1-(3-(4-amino-8- fluoro-6...)
Affinity DataIC50: 1.00E+4nMAssay Description:CVF-Bb complex is prepared from purified cobra venom factor (1 μM); human Complement factor B and human Complement factor D are available from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
Go to US Patent