BDBM489613 1-(4-(4-amino-8- fluoro-6,7-dimethoxy- quinazolin-2-yl)- piperazin-1-yl)-2- ((2S,3aS,7aS)-octa- hydro-1H-indol-2- yl)ethan-1-one hydrochloride::US10961252, Cmp No. 3::US11248000, Cmp No. 3

SMILES COc1cc2c(N)nc(nc2c(F)c1OC)N1CCN(CC1)C(=O)C[C@@H]1C[C@@H]2CCCC[C@@H]2N1

InChI Key InChIKey=KWUFRYONNXBYSP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 489613   

TargetComplement factor B(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM489613(US10961252, Cmp No. 3 | 1-(4-(4-amino-8- fluoro-6,...)
Affinity DataIC50: 1.00E+3nMAssay Description:CVF-Bb complex is prepared from purified cobra venom factor (1 μM); human Complement factor B and human Complement factor D are available from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
Go to US Patent

TargetCobra venom factor/Complement factor B/Complement factor D(Monocled cobra)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM489613(US10961252, Cmp No. 3 | 1-(4-(4-amino-8- fluoro-6,...)
Affinity DataIC50: 1.00E+3nMAssay Description:CVF-Bb complex is prepared from purified cobra venom factor (1 μM); human Complement factor B and human Complement factor D are available from a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
Go to US Patent